Abstract: In clinic, rare disease practice faces several problems, such as, frequent diagnosis errors, non-standardized treatment, and ineffective in preventing recurrence. In this paper, from the perspective of strengthening the rare disease teaching, we preliminarily explored how to improve the medical students’ cognitive level of rare disease by taking multiple measures, such as, delivery of selected teaching contents, application of diversity teaching methods and participation in clinical practice.

Key words: rare disease, medical genetics, teaching