Abstract: Objective To extensively evaluate the method of simultaneous determination of intra-gastric pressure (IGP) in perfusion nutrient load test (PNLT) in HS. Methods 30 HS were recruited. All HS were received simultaneous determination of IGP in PNLT. The barostat study was completed in another day. Visual analogue scale (VAS) was used to evaluate satiety during simultaneous determination of IGP in PNLT and the barostat study. Finally, all totally data were collected and analyzed. Results Pressure and volume of different satiety evaluated by VAS had significant correlation between the two methods respectively；IGP at maximal satiety was significantly correlated with peak accommodation volume and meal induced relaxation volume by the barostat study (P<0.05)；Maximal perfusion volume has significantly correlated with gastric postprandial averaged volume by the barostat study (P<0.05). Conclusions The method of simultaneous determination of IGP in PNLT has excellent feasibility, safety and reliability, and could be useful for evaluating proximal stomach function.

Key words: liquid nutrient , load test, proximal stomach