Abstract: The disease caused by Dengue virus is an acute life-threatening mosquito-borne infectious disease. So far, an effective and safe vaccine for dengue is not yet available. Recently a new virus-like particles vaccine can be capable of inducing the vaccinated mice to produce neutralizing antibody, and long-lasting virus-specific memory T lymphocytes. What more, it also can be widely explored by using yeast expression system. Its special priorities make it become a hopeful ideal dengue vaccine.

Key words: dengue virus, virus-like particles, vaccine, mosquito-borne infectious disease