Abstract: Objective To investigate the clinical pathological characteristics of different age patients with renal malignant tumor. Methods We analyzed the clinical and pathological data of 2,268 patients with renal malignant tumor admitted in PUMC hospital between 2002 and 2012. Patients were grouped according to age and pathological type. Results Among the 2,268 RCC patients, there were 260（11.5%），1178（51.9%），and 830（36.6%） patients aged <40, 40~59 and over 60 years old respectively. There were no significant differences in tumor size, and TNM stage by age group. However, patients <40 years old were significantly more likely to present with symptomatic tumors. There were no significant differences in histology by age; The surgical treatment of kidney cancer patients of different age groups was in different ways and the percentage of patients treated with partial nephrectomy declined with age. Conclusions the health examination of the youth crowd should be strengthened. the main form of treatment for kidney cancer is radical surgery, but we should pay attention to nephron sparing surgery.

Key words: renal cancer, Age factors, pathological