Basic & Clinical Medicine ›› 2013, Vol. 33 ›› Issue (1): 19-13.

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Loop-mediated isothermal amplification technology and its application in pathogenic microorganism detection

  

  • Received:2012-11-02 Revised:2012-11-19 Online:2013-01-05 Published:2012-12-25

Abstract: Loop-mediated isothermal amplification (LAMP) technology is a novel rapid nucleic acid isothermal amplification technology developed in recent years. Because of its high effiency, rapidity, specificity, and simplicity, scientists believe it will be a common amplification technology replacing the conventional PCR method. This paper briefly reviews the principle of the technology, techinical characteristics, progress, and its application in pathogenic microorganism detection.