Abstract: Gestational diabetes mellitus is the diabetes firstly found or occurring after pregnancy, which is the one of high risk states in pregnancy. However, its etiology and pathogenesis is not very clear at present. Recent data suggest that various adipokines are dysregulated in gestational diabetes mellitus. These adipokines include adiponectin , leptin, retinol-binding protein 4, vaspin， resistin, visfatin, might be of pathophysiological and prognostic significance in these complications of pregnancy.