Abstract: Thermotherapy becomes another important cancer treatment apart from the surgery, radiotherapy, chemotherapy and biological therapy. Heat shock proteins and dendritic cells which influenced by hyperthermia, correlate with tumor immunology, and was studied from bench to bedside. According to these researches, the development of translational medicine in combination of thermotherapy and tumor immunology has been in concern, and may change the status in quo of the treatment of cancer.

Key words: Tumor thermotherapy, Tumor immunology, Heat shock proteins, Dendritic cells, Translational medicine