Abstract: Humanistic knowledge and humanistic spirit are embodied in biomedical research and clinical practice. However, most Chinese medical school curricula consist of few courses on medical humanities and social science. The medical humanistic research and teaching ought to be improved. Many medical students are lack of critical thinking. The author suggests that medical schools should create a humanistic climate with qualified teachers to dissemination of a broad range of humanistic knowledge by using a problem-based teaching style. Medical students arm the instilled humanistic knowledge into both humanistic and scientific spirit and strengthen the ideal of medical profession.