Abstract: Objective We aimed to establish all hepatocytes related reference ranges for normal children by investigating 8 parameters referred to children’s venous whole blood in Heilongjiang Province. Methods Fasting venous blood samples of 3 866 healthy children aged 8 to 16 (1 837 male and 2 029 famale)were taken into EDTA-K2 anticoagulation tube, and the related reference values were measured by Sysmex XT-1800i hematoanalyzer. Software SPSS 15.0 was used for statistical analysis to descript the deviations between ages、races and regions. Results The means(reference ranges) of venous blood of 3866 health children in the Heilongjiang Province were as follows: White blood cells count to 6.9 (3.9～9.9)×109/L,Red blood cells count to 5.0 (4.2～5.8)×1012/L for male and 4.6 (4.0～5.2)×1012/L for female,the hemoglobin concentration was 146(124～168)g/L for male and 135(117～153)g/L for female, the Hematocrit is 43.9%(37.5%～50.5%) for male and 41.2%(36.4%～46.0%) for female, the Mean corpuscular volume was 88(80～97)fl, the mean corpuscular hemoglobin was 29(25～33)pg，the mean corpuscular hemoglobin concentration was 329(311～347）g/L，the platelet count was 277(161～393)×109/ L .Among health children, when compared with Korean ethnic minority group, all indexes like RBC、HCT、MCV and PDW of Han nationality did not show any differences with statistical significance. While there were remarkably differences on WBC、HGB、MCH、MCHC and PLT( P<0.05).Comparing between different ages and groups, all parameters except WBC presented with significant differences (P<0.05), positive correlation was found between RBC、HGB、HCT、MCV、MCH and age, negative correlation was found between MCHC、PLT and age. Conclusions Basic data bank for reference ranges of venous blood of healthy children in Heilongjiang Province had been initially established .And the differences were found among different ages、nations and regions of the children aged 8 to 16 is of great value in clinical purposes.

Key words: health children, Han nationality, Korean ethnic minority group, venous blood, blood cell parameters.