Abstract: Object: To explore the clinical specialty of stroke in Mongolian family .Methods: The pedigree was analyzed along with physical examination, stroke patients were been diagnose by CT or MRI, pick sample of blood 10ml to check the correlative physiological and biochemical criterion and gene research. Result:This family has 137 individuals, and including 10 strock patients 16 hypertension/ hyperlipoidemia patients, the result of blood fat diagnose indicated that the triglyceride’s and total cholesterol’s means of patients is higher than control group（p＜0.05） ,and the HDL is lower than control group（p＜0.05）. Conclusion: The abnormity of blood fat and hypertension are main reason of the stroke.