Basic & Clinical Medicine ›› 2023, Vol. 43 ›› Issue (3): 468-475.doi: 10.16352/j.issn.1001-6325.2023.03.468

• Clinical Sciences • Previous Articles     Next Articles

Prevalence and influencing factors of cognitive dysfunction among inpatients in Geriatrics Department of a hospital in Yunnan Province

DAI Jingrong1,2, LI Jie1,2, HE Xu1,2, LI Yang2, LI Yan1,2*   

  1. 1. School of Medicine, Kunming University of Science and Technology, Kunming 650500;
    2. Department of Geriatrics Medicine, the First People's Hospital of Yunnan Province, Yunnan Branch of National Clinical Research Center for Geriatric Diseases, Clinical Research Center for Geriatric Diseases of Yunnan Province, Dong Birong Expert Workstation, Kunming 650032, China
  • Received:2021-11-01 Revised:2022-04-19 Online:2023-03-05 Published:2023-02-27
  • Contact: *

Abstract: Objective To investigate the prevalence of cognitive dysfunction among inpatients in Geriatrics Depart- ment of a hospital in Yunnan Province, and to analyze the influencing factors of cognitive dysfunction of the elderly.Methods A total of 2 216 admitted patients(≥60 years old) in the Department of Geriatrics of a hospital in Yunnan Province from September 2018 to August 2021 were recruited as the subjects. General data of the patients were collected. Comprehensive geriatric assessment was conducted by an internet-based platform of the Comprehensive Geriatric Assessment developed by the Department of Geriatrics of Yunnan First People's Hospital, among which cognitive function was assessed by the Mini-Mental State Examination(MMSE)phenotype. Results Among 2 216 patients, 1 087(49.1%) had normal cognitive function, 639(28.8%) had mild cognitive impairment, 285 (12.9%) had moderate cognitive impairment and 205 (9.3%) had severe cognitive impairment. According to multivariate Logistic regression analysis, increased age [OR=1.026,95% CI(1.015, 1.037),P< 0.001], vision decline[OR=1.290,95% CI(1.002, 1.662),P< 0.05], empty nest[OR=1.433,95% CI(1.009, 2.034),P< 0.05], family support disorder[OR=1.436,95% CI(1.120, 1.842),P< 0.05], insomnia [OR=1.380,95% CI(1.095, 1.740),P< 0.05] and suffered chronic obstructive pulmonary disease [OR=1.234,95% CI(1.008, 1.512),P< 0.05) were the risk factors for cognitive function in the elderly, while the individuals mainly engaged in mental activities[OR=0.678,95% CI(0.540,P< 0.05).0.852, P< 0.001], education experience of primary school[OR=0.613,95% CI(0.485,0.776,P<0.001], secondary school[OR=0.670,95% CI(0.534, 0.839), P< 0.001) and university degree or above [OR=0.555,95% CI(0.410, 0.751),P< 0.001] were protective factors. Conclusions The prevalence of cognitive dysfunction in elderly hospitalized patients is high and closely related to a variety of factors. Specific intervention of related factors is of great significance for the early prevention of cognitive impairment in the elderly.

Key words: cognitive impairment, geriatric syndrome, Comprehensive Geriatric Assessment, influencing factor, inpatient

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