Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (11): 1767-1770.doi: 10.16352/j.issn.1001-6325.2022.11.1767

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Research progress on the role of secretory protein Metrnl in different diseases

ZHANG Lan-yue, ZHANG Xue-dong*   

  1. Department of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University, Chongqing 400000, China
  • Received:2021-05-24 Revised:2021-11-12 Online:2022-11-05 Published:2022-11-01
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Abstract: Metrnl is a new cytokine with homologous orignination from neurotrophic factor Meteorin. Meanwhile, as a secreting protein, its gene and products show low tissue specificity and is widely expressed in different tissues of host. Similar to neurotrophic factor, adipocytokines, inflammatory factor and muscle factor, the protein plays a role in neural development, immune inflammatory response and metabolism and so on.

Key words: Meteorin-like protein(Metrnl), neurotrophic factor, energy metabolism, insulin resistance, immunoregulation

CLC Number: