Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (3): 520-524.doi: 10.16352/j.issn.1001-6325.2022.03.011

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Progress in the study of the epigenetic regulation of cardiac hypertrophy

ZHENG Jing-jing1, BU Ning1, ZHAO Zhao1, ZHANG Jia-jing2, YU Hui1, ZHAO Yu-hang1*   

  1. 1. Baotou Medical College,Baotou 014000;
    2. Inner Mongolia Baotou Steel Sanatorium,Baotou 014000,China
  • Received:2021-07-15 Revised:2021-11-15 Online:2022-03-05 Published:2022-03-04
  • Contact: *

Abstract: Myocardial hypertrophy is an independent risk factor for various serious cardiovascular diseases.Epigenetic mechanisms such as DNA methylation, histone modification, and RNA methylation are involved in the pathogenesis and development of cardiac hypertrophy.To understanding the role of epigenetic regulation on cardiac hypertrophy contributes to to development of an effective protocol and provide scientific basis for the prevention and early treatment of cardiac hypertrophy.

Key words: myocardial hypertrophy, epigenetics, noncoding RNA, DNA methylation, histone modification

CLC Number: