基础医学与临床 ›› 2009, Vol. 29 ›› Issue (11): 1224-1227.

• 短篇综述 • 上一篇    下一篇

血管中心型胶质瘤的研究进展

张遥 窦万臣   

  1. 中国医学科学院 北京协和医学院 北京协和医院 中国医学科学院 北京协和医学院 北京协和医院 神经外科
  • 收稿日期:2009-02-17 修回日期:2009-03-11 出版日期:2009-11-20 发布日期:2009-11-20
  • 通讯作者: 窦万臣

Advances on Research of Angiocentric Glioma

Yao ZHANG, Wan-chen DOU   

  1. PUMC Hospital, CAMS&PUMC Dept. of Neurosurgery, PUMC Hospital, CAMS&PUMC
  • Received:2009-02-17 Revised:2009-03-11 Online:2009-11-20 Published:2009-11-20
  • Contact: Wan-chen DOU

摘要: 血管中心型胶质瘤是一种近年来新认识到的致癫痫的脑胶质瘤,目前全世界已报道的病例很少。该肿瘤在临床上主要表现为药物难治性癫痫,组织学特点为形态单一的双极肿瘤细胞以各级血管为中心排列。在影像学上该肿瘤具有T1像皮质呈弥漫性或花边样(rimlike)高密度,T2像呈蒂状(stalklike)延伸至脑室等显著特征。2007年,WHO将其纳入中枢神经系统肿瘤新的分类系统中。

关键词: 血管中心型胶质瘤 药物难治性癫痫

Abstract: Angiocentric Glioma has been newly identified as an epilepsy associated tumor recently. Up to now, such cases that have been reported are still scarce. The tumor causes drug-resistant epilepsy. On histological findings, monomorphous bipolar tumor cells are arranged around vessels. Imaging studies show that the tumor is diffused or rimlike hyperintensity on T1-weighted SE sequences and a stalklike extension to the ventricle on T2-weighted sequences. The World Health Organization listed this new entity in its fourth edition of the WHO classification of tumors of the central nervous system published in 2007.

Key words: Angiocentric Glioma, drug-resistant epilepsy