Abstract: Objective To investigate the prevalence of hyperuricemia and its associated factors including dietary and Metabolic Syndrome in populations of Dongcheng district in Beijing. Methods A cross-sectional study of hyperuricemia was carried out in volunteers who had diabetes screening from 2003 to 2004. The prevalence of hyperuricemia was calculated in the population. Applying the form of food frequency to know the intake of nutritional-rich dietary.Results The prevalence of hyperuricemia in this population was 4.3%, and in male and female were 10.7% and 1.07% respectively.Bivariate and rank analysis found that hypertriglyceride were associated with increased prevalence of hyperuricemia (P<0.01) .There was significantly relativity with impaired glucose regulation in female, whereas no relativity in male.Multivariate logistic regression analysis found that male, obesity,waist obesity, hypertriglyceride, hypercholesterolemia were significantly associated with prevalence of hyperuricemia(P<0.01),HDL-c and fasting glucose were negative significantly association, but the products of nutrient buillon,seafood, animal organs,mushroom were no significantly associated whether men or women.Conclusions Male gender,obesity, waist obesity and hypercholesterolemia, hypertriglyceride may be associated with increased risk of hyperuricemia.