基础医学与临床 ›› 2016, Vol. 36 ›› Issue (12): 1728-1732.
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王琥1,张明2,曾凡慧3
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摘要： 精原干细胞（SSC）在睾丸曲细精管内微环境的精确调控下，只能单向分化为精子。然而，SSC可在特定条件下转化为多能干细胞，甚至直接重编程转分化为功能性终末分化细胞。该特殊潜能使其在再生和精准医学领域具有很好的运用前景。
关键词: 精原干细胞, 转化, 转分化
Abstract: Under the testicular seminiferous tubule microenvironment control, spermatogonial stem cells (SSC) can only differentiate into sperms. Recent studies have shown that SSC may reprogram into pluripotent stem cells, or even directly reprogramming transdifferentiation into functional terminally differentiated cells under certain conditions in vitro. This potential of SSC makes it promise in the regenerative medicine and precise medicine application.
Key words: spermatogonial stem cell, conversion, transdifferentiation
王琥 张明 曾凡慧. 精原干细胞体外转化和转分化的研究进展[J]. 基础医学与临床, 2016, 36(12): 1728-1732.
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