基础医学与临床 ›› 2011, Vol. 31 ›› Issue (7): 839-842.

• 短篇综述 • 上一篇    下一篇

蛋白质组学技术在宫颈癌研究中的应用进展

栾力,程玉峰   

  1. 山东大学齐鲁医院
  • 收稿日期:2010-06-08 修回日期:2010-11-26 出版日期:2011-07-05 发布日期:2011-07-05
  • 通讯作者: 程玉峰 E-mail:qlcyf@163.com
  • 基金资助:
    省自然科学基金

Advances in the Application of Proteomics in Cervical Carcinoma Research

Li LUAN,Yu-feng CHENG   

  1. Qilu Hospital,Shandong University
  • Received:2010-06-08 Revised:2010-11-26 Online:2011-07-05 Published:2011-07-05
  • Contact: Yu-feng CHENG E-mail:qlcyf@163.com

摘要: 蛋白质组学技术已广泛应用于肿瘤的发生机制、肿瘤特异性标志物的筛选和鉴定、疗效评价等方面的研究,也应用于宫颈癌的早期诊断、临床分期、筛选治疗靶点等方面的探索,从蛋白质组水平揭示了宫颈癌蛋白质表达谱的变化,为宫颈癌诊断和治疗的发展提供了可靠的理论依据。

关键词: 蛋白质组学, 宫颈癌, 应用

Abstract: Proteomic technology has been widely used in the research of medical sciences, including the study of the pathogenesis of carcinoma, discovery and identification of novel biomarkers and evaluating the response to treatment, as well as in the application of early diagnosis, clinical pathologic stages and screening therapeutic targets in cervical carcinoma. In the aspect of cervical carcinoma, many reports have demonstrated the differently expressed proteins from the proteome level, and these results provide reliable theoretic base for well understanding of the diagnosis and treatment in cervical carcinoma.

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