基础医学与临床 ›› 2020, Vol. 40 ›› Issue (11): 1534-1536.

• 临床研究 • 上一篇    下一篇

合并血友病患者神经外科围术期处理

雷成, 梅弘勋, 韩如泉*   

  1. 首都医科大学附属北京天坛医院 麻醉科, 北京 100070
  • 收稿日期:2020-07-23 修回日期:2020-09-22 出版日期:2020-11-05 发布日期:2020-10-30
  • 通讯作者: * ruquan.han@ccmu.edu.cn

Perioperative management for neurosurgery patients complicated with hemophilia

LEI Cheng, MEI Hong-xun, HAN Ru-quan*   

  1. Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
  • Received:2020-07-23 Revised:2020-09-22 Online:2020-11-05 Published:2020-10-30
  • Contact: * ruquan.han@ccmu.edu.cn

摘要: 目的 探讨血友病患者在神经外科围术期麻醉相关处理的方法经验。方法 回顾收集整理合并血友病行神经外科手术患者的临床资料,分析总结疾病特点和临床经验。结果 2例患者均为血友病A型男性患者。分别行颅骨修补术和复发颅脑肿瘤切除术。术前多学科会诊,指导给予凝血因子补充。术中严密监测出血情况,其中1例术后伤口渗血急诊开颅行血肿清除。术后患者安返病房,并且规律给予凝血因子补充替代治疗,监测凝血指标,恢复良好。结论 血友病是严重的遗传性出血性疾病,围术期的多学科合作、监测凝血功能状态、适时补充凝血因子、精细化麻醉管理,是患者围术期安全的重要保证。

关键词: 血友病, 围术期麻醉管理, 神经外科

Abstract: Objective To explore the methods and experience of anesthesia related management in perioperative neurosurgery patients complicated with hemophilia. Methods The clinical data of patients with hemophilia undergoing neurosurgery were collected. Results Two patients underwent neurosurgery were diagnosed as hemophilia properatively. Multidisciplinary consultation was conducted. Coagulation factor Ⅷ was perioperatively infused. Conclusions Hemophilia is a serious hereditary hemorrhagic disease. Perioperative multidisciplinary intervention, monitoring of coagulation function, timely supplementation of coagulation factors and fine anesthesia management are important for perioperative safety of patients.

Key words: hemophilia, perioperative anesthesia management, neurosurgery

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