基础医学与临床 ›› 2014, Vol. 34 ›› Issue (2): 274-277.

• 短篇综述 • 上一篇    下一篇

载脂蛋白A5在调节三酰甘油代谢中的作用

谢羽飞,赵水平   

  1. 中南大学湘雅二医院
  • 收稿日期:2013-04-11 修回日期:2013-06-21 出版日期:2014-02-05 发布日期:2014-01-13
  • 通讯作者: 赵水平 E-mail:zhaosp@medmail.com.cn

Roles of apolipoprotein A5 in regulation of triglyceride metabolism

  • Received:2013-04-11 Revised:2013-06-21 Online:2014-02-05 Published:2014-01-13

摘要: 载脂蛋白A5调节三酰甘油代谢的可能机制是:1)直接或间接地激活脂蛋白脂酶,加速富含三酰甘油脂蛋白的脂解;2)抑制极低密度脂蛋白合成和分泌;3)加速肝脏对脂蛋白残粒的摄取。进一步明确载脂蛋白A5在调节三酰甘油代谢中的作用,为心脑血管疾病的诊治提供新思路。

关键词: 关键词:载脂蛋白A5, 三酰甘油, 富含三酰甘油的脂蛋白, 心脑血管疾病

Abstract: Apolipoprotein A5 adjusting triglyceride metabolism possible mechanisms are: 1) directly or indirectly, activating lipoprotein lipase, accelerated lipolysis rich in triglycerides; 2) inhibit the synthesis and secretion of very low density lipoprotein; 3)speed up the liver for lipoprotein remnants of grain intake. Further clarify the role of apolipoprotein A5 in regulating metabolism of triglyceride, keen cerebrovascular disease for clinical diagnosis and treatment to provide new ideas.

Key words: Key words:apolipoprotein A5, triglyceride, TG-rich lipoprotein, cardiovascular and cerebrovascular diseases