基础医学与临床 ›› 2014, Vol. 34 ›› Issue (11): 1570-1573.
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田清平1,唐朝枢2,庞永正3,刘梅林1
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摘要: Betatrophin是一种新发现的影响糖脂代谢的因子。人类Betatrophin基因定位于染色体19p13.2,鼠类该基因定位于9号染色体,这是一个高度保守的基因,人类Betatrophin的氨基酸序列与鼠类有73%同源性,82%相似性,主要表达在肝脏和脂肪组织,对糖脂代谢有重要影响。
关键词: Betatrophin, 糖尿病, 脂代谢紊乱
Abstract: Betatrophin is a novel factor which regulate the glucose and lipid metabolism. Human betatrophin is located at chromosomal position 19p13.2, and the murine gene is present on chromosome 9. This is a highly conserved gene. Human betatrophin protein shows 73% identity and 82% similarity to the murine protein. It is predominantly expressed in liver and fat, and plays a great role in glucose and lipid metaboslim.
Key words: betatrophin, diabetes mellitus, dyslipidemia
中图分类号:
R589
田清平 唐朝枢 庞永正 刘梅林. Betatrophin是一种新的糖脂代谢影响因子[J]. 基础医学与临床, 2014, 34(11): 1570-1573.
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