基础医学与临床 ›› 2013, Vol. 33 ›› Issue (7): 923-926.
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何金花,黎毓光
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摘要: 非编码RNA,包括以miRNA、siRNA和piRNA等为代表的短小RNA和长链非编码RNA。长链非编码RNA,有别于其他小分子非编码RNA,是目前非编码RNA研究的热点。随着研究的不断推进,人们发现lncRNA与物种进化、胚胎发育、物质代谢以及肿瘤发生等都有着密切的联系。microRNA是一类长度为19~23个核苷酸的内源性非编码 RNA,可以在转录水平或转录后水平调节基因的表达。
关键词: 长链非编码RNA, 微小非编码RNA, 病毒, 进展
Abstract: Noncoding RNA,including miRNA,siRNAand piRNA as the representative of the short RNA and long chain non coding RNA.long non-coding RNAs (lncRNAs) are hot spots which are different from other smaller non-coding RNAs. Through researches, lncRNAs have been found to affect species evolution, embryonic development, metabolism and tumorigenesis. MicroRNAs (miRNAs) are a class of small noncoding RNAs that control gene expression by targeting mRNAs and triggering either translation repression or RNA degradation.
Key words: long non-coding RNAs, small non-coding RNA, virus, trend study
何金花 黎毓光. 长链非编码RNA与病毒和微小非编码RNA关系的研究进展[J]. 基础医学与临床, 2013, 33(7): 923-926.
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