基础医学与临床 ›› 2013, Vol. 33 ›› Issue (4): 463-466.

• 研究论文 • 上一篇    下一篇

实验性加压疼痛对健康人群疼痛相关字词注意偏向的影响

罗艳琳1,王禹2,3,崔敏2,3,冯雪岩2,3,窦鑫2,3,柳金金2,3,李俊发3   

  1. 1. 首都医科大学神经生物学系 北京神经科学研究所
    2.
    3. 首都医科大学
  • 收稿日期:2012-05-09 修回日期:2012-07-05 出版日期:2013-04-05 发布日期:2013-03-15
  • 通讯作者: 李俊发 E-mail:junfali@ccmu.edu.cn
  • 基金资助:
    首都医科大学基础临床合作课题

The effect of tourniquet pain on attentional bias in healthy individuals

  • Received:2012-05-09 Revised:2012-07-05 Online:2013-04-05 Published:2013-03-15
  • Contact: Jun-fa LI E-mail:junfali@ccmu.edu.cn
  • Supported by:
    Capital medicial university basic-clinical project

摘要: 目的 观察实验性加压疼痛对疼痛相关字词注意偏向的影响。方法 32名健康大学生左上臂捆绑止血带,在加压疼痛(实验1)或无加压(实验2)条件下,对5类疼痛相关字词进行改良Stroop认知任务。记录受试者对字词的反应时、错误率以及疼痛强度与不适度。结果 26.6 kPa加压可诱发受试者出现中重度疼痛。无加压实验中,男性对正性字词的反应速度明显快于女性(P<0.001)。加压疼痛实验中,男性对情感性、感觉性疼痛字词和正性字词的反应速度显著快于女性(P<0.001)。表明疼痛影响了男性的认知速度。同时,加压疼痛使受试者反应错误率明显升高(P<0.05),其中社会威胁性字词错误率升高显著(P<0.05)。偏向指数也显示,疼痛条件下对社会威胁性字词的显著注意偏向(P<0.05)。结论 实验性中重度疼痛诱发受试者对社会性威胁字词出现注意偏向。

关键词: 加压疼痛, 字词认知, 注意性偏向, 改良Stroop 任务

Abstract: Objective To investigate the effect of experimental tourniquet pain on attentional bias towards pain-related words. Methods The tourniquet was tied to the left upper limb of 32 healthy college students, while tourniquet inflating (experiment 1) or not (experiment 2), all subjects were asked to finish the modified Stroop tasks including five kinds of pain-related words. The reaction time, the error rate of recognition task and the pain intensity and distress were recorded. Results Moderate to severe pain was induced by tourniquet inflating. In experiment 1, the reaction time for positive words of male was significantly shorter than female (P<0.001). In experiment 2, for sensory pain words, affective pain words and positive words, the reaction time of female was shorter than male significantly (P<0.001). This showed that pain has accelerated the cognitive reaction speed of male. The error rate was increased obviously in the condition of tourniquet pain (P<0.05), particularly for social threaten words (P<0.05). The bias index showed significant cognitive bias for the social threat words under condition of pain (P<0.05). Conclusion An attentional bias was found towards to social threat words in healthy subjects in moderate pain condition.

Key words: tourniquet pain, word recognition, attentional bias, modified Stroop task