基础医学与临床 ›› 2012, Vol. 32 ›› Issue (8): 875-879.

• 妊娠糖尿病专题 • 上一篇    下一篇

脂肪细胞因子与妊娠期糖尿病

刘冰   

  1. 北京友谊医院
  • 收稿日期:2012-05-16 修回日期:2012-06-14 出版日期:2012-08-05 发布日期:2012-07-17
  • 通讯作者: 刘冰

Adipokines and gestational diabetes mellitus

  • Received:2012-05-16 Revised:2012-06-14 Online:2012-08-05 Published:2012-07-17

摘要: 妊娠期糖尿病严重威胁母婴健康,是社会公共卫生事业的关注重点。目前妊娠期糖尿病的发病机制尚未完全阐明, 近年来脂肪因子在其发病机制中的作用备受关注。这些脂肪因子包括脂联素、瘦素、视黄醇结合蛋白-4、Visfatin、Vaspin、抵抗素和chemerin等。

Abstract: Gestational diabetes mellitus is the diabetes firstly found or occurring after pregnancy, which is the one of high risk states in pregnancy. However, its etiology and pathogenesis is not very clear at present. Recent data suggest that various adipokines are dysregulated in gestational diabetes mellitus. These adipokines include adiponectin , leptin, retinol-binding protein 4, vaspin, resistin, visfatin, might be of pathophysiological and prognostic significance in these complications of pregnancy.