基础医学与临床 ›› 2011, Vol. 31 ›› Issue (3): 334-338.
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李爱玲,修瑞娟
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摘要： 内质网应激（ERS）可诱导多种细胞凋亡，与疾病发生发展密切相关。钙联蛋白（CNX）是内质网中重要的类凝集素分子伴侣，通过参与未折叠蛋白反应，募集凋亡相关因子、激活IRE1-JNK激酶等途径，调控ERS诱导的凋亡。本文就其研究现状进行阐述。
关键词: 内质网应激, 钙联蛋白, 细胞凋亡
Abstract: Endoplasmic reticulum stress(ERS) could induce apoptosis of mamy kinds of cell, that is relative closely with disease development. Calnexin, a kind of chaperon in endoplasmic reticulum, could modulate the apoptosis induced by ERS via several pathway invovling UPR, recruiting apoptosis-related factor, activating IRE1-JNK, and so on.
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Q255
李爱玲 修瑞娟. 钙联蛋白调控内质网应激诱导的细胞凋亡 [J]. 基础医学与临床, 2011, 31(3): 334-338.
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链接本文: http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/
http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/Y2011/V31/I3/334
