基础医学与临床 ›› 2011, Vol. 31 ›› Issue (3): 308-311.

• 研究论文 • 上一篇    下一篇

食管贲门癌患者术后空腹血糖水平异常升高不利于术后恢复

郑庆锋1,姚震旦1,2,李少雷1,2,吴楠1,2,陈晋峰1,2,张力建1,2,杨跃1   

  1. 1. 北京大学 临床肿瘤学院 北京肿瘤医院暨北京市肿瘤防治研究所
    2.
  • 收稿日期:2010-12-10 修回日期:2011-01-12 出版日期:2011-03-05 发布日期:2011-03-14
  • 通讯作者: 杨跃 E-mail:zlyangyue@bjmu.edu.cn

The elevated fasting palsma glucose levels is not conducive to postoperative recovery in patients with esophageal and cardiac cancer

ZHENG Qing-feng 1,Yao Zhen-dan 2,2,Li Shao-lei 2,Wu Nan 2,Chen Jin-feng 2,2,Zhang Li-jian 2,YANG Yue 1   

  • Received:2010-12-10 Revised:2011-01-12 Online:2011-03-05 Published:2011-03-14
  • Contact: YANG Yue E-mail:zlyangyue@bjmu.edu.cn

摘要: 目的 研究食管贲门癌患者术后空腹血糖水平异常升高与术后恢复的关系。方法 根据1996年1月~2009年10月在北京大学临床肿瘤学院胸外二科手术治疗的196例食管贲门癌患者,分别就术前、术后空腹血糖水平记录以及术后并发症记录,采用χ2检验对数据进行分析。结果 (1)食管贲门癌患者术后空腹血糖水平升高的患者明显多于术前,分别为115例及38例;(2)患者术前血糖空腹水平的升高与术后并发症的发生无统计学关联;(3)术后空腹血糖水平升高的患者,术后严重感染及吻合口瘘发生率明显升高(p<0.05,p<0.01)。结论食管贲门癌患者术后空腹血糖水平异常升高不利于术后恢复,术后有效控制空腹血糖可能促进患者术后恢复。

关键词: 食管贲门癌, 术后空腹血糖, 术后恢复

Abstract: Objective To study the realation of elevated fasting plasma glucose levels after operation and postoperative recovery in patients with esophageal and cardiac cancer. Methods From January 1996 to October 2009, 196 cases of surgical treatment in the thoracic surgery II of Peking University School of Oncology were recruited, observing and recording fasting plasma glucose levels before and after operation and postoperative complications . χ2 test was used to analyze the data. Results (1) The patients with elevated fasting glucose levels after operation were significantly more than those before operation ,respectively 115 cases and 38 cases; (2) No significant correlation was found between elevated fasting plasma glucose levels in preoperative patients and postoperative complications; (3) In postoperative patients with elevated fasting glucose levels, the incidence of postoperative severe infection and anastomotic leakage was significantly higher. p values were 0.028 and 0.002. Conclusion he elevated fasting plasma glucose levels in the patients of esophageal and cardiac cancer after operation is not conducive to postoperative recovery .The effective control of postoperative fasting plasma glucose to normal levels may contribute to patients recovery.

Key words: esophageal and cardiac cancer, fasting plasma glucose after operation, postoperative recovery

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