基础医学与临床 ›› 2011, Vol. 31 ›› Issue (12): 1363-1365.

• 研究论文 • 上一篇    下一篇

意识指数与脑电双频指数监测靶控丙泊酚全麻诱导时镇静深度的比较

辛鑫1,黄宇光2,赵晶2   

  1. 1. 中国医学科学院 北京协和医院
    2. 中国医学科学院 北京协和医学院 北京协和医院 麻醉科
  • 收稿日期:2010-11-01 修回日期:2011-05-11 出版日期:2011-12-05 发布日期:2011-12-05
  • 通讯作者: 赵晶 E-mail:zhaojingpumc@yahoo.com.cn

Comparison between the Index of Consciousness and the Bispectral Index during Propofol Target-controlled Infusion Anaesthesia Induction

  • Received:2010-11-01 Revised:2011-05-11 Online:2011-12-05 Published:2011-12-05

摘要: 目的 探讨意识指数(Index of Consciousness,IOC)与脑电双频指数(Bispectral Index, BIS)相比,靶控丙泊酚全麻诱导时用于监测镇静深度的相关性。方法 研究纳入行普外或妇科手术的患者30例,靶控丙泊酚全麻诱导期间,同时监测IOC和BIS。记录镇静评分(observers assessment of alertness/sedation scale, OAA/S)由5分逐级降低至1分时,每次OAA/S 评分即刻的IOC及BIS值,以及相应点的丙泊酚效应室浓度。结果 IOC、BIS与OAA/S的相关系数r分别为0.988和0.986(P<0.001),BIS与IOC的相关系数r为0.997(P<0.001)。结论 IOC用于靶控丙泊酚全麻诱导时的镇静深度监测,与BIS具有良好的相关性。

关键词: 意识指数, 脑电双频指数, 麻醉镇静深度, 丙泊酚, 靶控

Abstract: Objective To compare a new level of consciousness monitor, called the index of consciousness (IOC) with the bispectral index (BIS) during propofol target-controlled infusion (TCI) anaesthesia induction. Methods After ethical committee approval and written patient consent, data from 30 patients were recorded. All patients were induced with propofol target-controlled infusion (TCI), until the Observer’s Assessment of Alertness and Sedation (OAAS) scale level 1 was reached, and then IOC and BIS were calculated during OAAS 5~1. Results IOC (0.988, P<0.001) and BIS (0.986, P<0.001) positively correlated with OAAS, while IOC positively correlated with BIS (0.997, P<0.001). Conclusions IOC has the good correlation with BIS during propofol target-controlled infusion (TCI) anaesthesia induction.

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