基础医学与临床 ›› 2010, Vol. 30 ›› Issue (2): 215-218.

• 短篇综述 • 上一篇    下一篇

人脐带间充质干细胞的生物学性质研究进展

范存刚 周景儒 张庆俊   

  1. 北京大学人民医院 北京大学人民医院
  • 收稿日期:2009-02-18 修回日期:2009-05-19 出版日期:2010-02-05 发布日期:2010-02-05
  • 通讯作者: 张庆俊

Progress in the study of biological characteristics of mesenchymal stem cells derived from human umbilical cord

Cun-gang FAN, Jing-ru ZHOU, Qing-jun ZHANG   

  1. People's Hospital, Peking University People's Hospital, Peking University
  • Received:2009-02-18 Revised:2009-05-19 Online:2010-02-05 Published:2010-02-05
  • Contact: Qing-jun ZHANG

摘要: 人脐带中富含间充质干细胞(MSCs)。这些细胞能表达多种间充质干细胞标志物及多种干细胞相关基因,能分化为3个胚层衍生的多种成熟细胞、合成多种营养因子和细胞因子、支持造血干细胞等细胞的增殖和功能,并具有低免疫原性。

Abstract: Recent research indictates that human umbilical cord is rich in mesenchymal stem cells. These cells have the potencies of expressing many surface markers of mesenchymal stem cell, differentiating into a variety of cells of three germ layers, synthesizing and secreting a set of trophic factors and other cytokines, and supporting the expansion and function of other cells hematopoietic stem cells and other cells. In addition, immunogenicity of these cells is realatively low.