关键词: 脂肪组织, 脂肪干细胞, 去分化脂肪细胞, 缺血性心脏病, 心力衰竭

Abstract: Ischemic heart disease leading to heart failure seriously affects the quality of patients'life. Stem cell transplantation has been proposed to be a promising therapy for ischemic heart disease. Adipose-tissue derived stem cells (ADSC)and Dedifferentiated FAT (DFAT) cells are able to differentiate into multiple cell lineages including cardiac myocytes. Transplantation of adipose-derived cells after myocardial infarction significantly improves heart function, reduces ventricular remolding. Hence, adipose-derived cells are emerging as a new sourse of adult stem cells for cardiovascular repair.

Key words: Adipose Tissue, Adipose-Tissue Derived Stem Cell, Dedifferentiated Adipocyte, Ischemic Heart Disease, Heart Failure