基础医学与临床 ›› 2008, Vol. 28 ›› Issue (3): 294-296.

• 短篇综述 • 上一篇    下一篇

胚胎干细胞增殖分化相关基因

姜开军 王菊 周宗瑶   

  1. 新疆石河子大学 新疆石河子大学 新疆石河子大学
  • 收稿日期:2007-03-02 修回日期:2007-08-13 出版日期:2008-03-25 发布日期:2008-03-25
  • 通讯作者: 周宗瑶

Related genes about embryonic stem cell's proliferation and differentiation

Kai-jun JIANG, Ju WANG, Zong-yao ZHOU   

  1. Department of Histology & Embryology, SHI HE ZI University School of Medicine Department of Histology & Embryology, SHI HE ZI University School of Medicine
  • Received:2007-03-02 Revised:2007-08-13 Online:2008-03-25 Published:2008-03-25
  • Contact: Zong-yao ZHOU

摘要: 胚胎干细胞是从早期胚胎内细胞团中分离得到的,可以长久维持对称性自我更新的未分化状态,也可以分化成几乎机体所有类型的细胞。多种基因参与了胚胎干细胞增殖分化的调节。现对胚胎干细胞增殖分化相关基因进行综述。

关键词: 胚胎干细胞, SOX2, NANOG, 生殖细胞核因子

Abstract: Embryonic stem cells,which are detached from inner cell mass(ICM), can maintain self-renewal undifferentiation status and differentiate into almost every type of cells. Lots of genes take part in the regulation of embryonic stem cell's proliferation and differen- tiation. In this paper, we review the related genes about embryonic stem cell's proliferation and differentiation, meantime draw off questions which need to be further illuminated.

Key words: embryonic stem cell, SOX2, NANOG, GCNF