基础医学与临床 ›› 2007, Vol. 27 ›› Issue (3): 293-297.

• 研究论文 • 上一篇    下一篇

单纯性肥胖症状胃肌电活动特征

常丽丽 姚树坤 王智凤   

  1. 河北医科大学第四医院消化内科
  • 收稿日期:2006-05-08 修回日期:2006-11-07 出版日期:2007-03-25 发布日期:2007-03-25
  • 通讯作者: 常丽丽

The characteristics of gastric myoelectical activity in ohese people

  

  • Received:2006-05-08 Revised:2006-11-07 Online:2007-03-25 Published:2007-03-25

摘要: 目的 探讨进餐前、后单纯性肥胖者的胃肌电活动特征。方法 采用Digitrapper双电极EGG记录仪记录41例单纯性肥胖者餐前和餐后胃肌电活动,以32例正常体重健康志愿者为对照。结果 ①空腹状态下,肥胖组正常慢波节律百分比显著低于正常体重组(55.52±15.7 vs 70.83±14.31,p<0.05);胃动过缓百分比显著高于正常体重组(17.07±10.88 vs 11.46±8.86,p<0.05);无节律百分比显著高于正常体重组(9.70±5.70 vs 5.75±4.14,p<0.01)。②进餐后,单纯性肥胖者正常慢波节律百分比仍显著低于正常体重组(53.19±17.77 vs 64.34±22.63,p<0.05);主功率和胃动过速百分比显著高于正常体重组(36.50±4.86 vs 32.24±6.25,19.93±11.62 vs 12.94±11.72,p<0.01 和p<0.05)。③肥胖组餐后功率及振幅增加值显著高于正常体重组(p<0.01);餐后、餐前功率比显著高于正常体重组(p<0.05)。结论 单纯性肥胖者空腹及餐后存在胃电节律异常,且餐后胃电主功率异常升高,可能是肥胖者胃动力亢进发生的电生理基础。

Abstract: Objective to explore the characteristics of gastric myoelectrical activity induced by meal in obese people. Methods 41 cases of obese subjects were investigated with Digitrapper electrogastrography(EGG) before and after test meal,32 healthy volunteers with normal body mass index were studied as control. Results before meal, the percentage of normal slow waves(N%)in obese group was lower than that in control subjects(55.52±15.7 vs 70.83±14.31, P<0.05); the percentage of bradygastria (B%) and the percentage of arhythmia (AR%) in obese group were higher than those in control group respectively (17.07±10.88 vs 11.46±8.86, 9.70±5.7 vs 5.75±4.14,P<0.05 and P<0.01). ②after meal, N% in the obese was lower than that of the control group (53.19±17.77 vs 64.34±22.63, P<0.05);DP and the percentage of tachygastria(T%) in the obese were higher than those in control group respectively (36.50±4.86 vs 32.24±6.25, 19.93±11.62 vs 12.94 ±11.72,P<0.01 and P<0.05). ③the increase of DP, amplitude and power ratio (PR) in the obese were significantly higher than those in control group (P<0.01 and P<0.05).Conclusion At fasting state and post-meal state, obese people have abnormalities in gastric myoelectrical activity. Abnormal gastric electrical activity and DP'increase after meal may be electrophysiological basis of gastric hypermotility in obese people.