基础医学与临床 ›› 2007, Vol. 27 ›› Issue (11): 1297-1299.

• 短篇综述 • 上一篇    下一篇

线粒体融合蛋白2与胰岛素抵抗

曲东明   

  1. 河北省人民医院 河北省老年医学重点实验室
  • 收稿日期:2006-12-30 修回日期:2007-01-25 出版日期:2007-11-25 发布日期:2007-11-25
  • 通讯作者: 曲东明

Mitofusin 2 and insulin resistance

  • Received:2006-12-30 Revised:2007-01-25 Online:2007-11-25 Published:2007-11-25

摘要: 摘要:线粒体融合蛋白2于1997年由北医教授陈光慧最初发现。迄今已发现该蛋白质具有促进线粒体融合、抑制细胞增殖、保护细胞免于凋亡等多种功能。目前,越来越多的证据表明该基因产物与胰岛素抵抗状态有关。

关键词: 线粒体融合蛋白, 胰岛素抵抗

Abstract: Abstrct:Mitofusin 2 was first found in 1997 by Kuang-Hueih Chen, a professor of Peking University. A lot of functions have been found about this protein, such as promoting mitochondria fusion, inhibiting cell proliferation and protecting cell avoid of apoptosis. Now, more and more evidence suggest it is involved in insulin resistance.

Key words: mitofusin, insulin resistance