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                                    02468The number of osteoclasts1)2)2)3)3)Control groupModel groupPUE-L groupPUE-H groupPUE-H+Disitertide group%u4e0e %uff23%uff4f%uff4e%uff54%uff52%uff4f%uff4c%u7ec4%u6bd4%u8f83%uff0c%uff11%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff1b%u4e0e %uff2d%uff4f%uff44%uff45%uff4c%u7ec4%u6bd4%u8f83%uff0c%uff12%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff1b%u4e0e %uff30%uff35%uff25%ue011%uff28%u7ec4%u6bd4%u8f83%uff0c%uff13%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%u3002%uff11%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff43%uff4f%uff4e%uff54%uff52%uff4f%uff4c%uff47%uff52%uff4f%uff55%uff50%uff1b%uff12%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff2d%uff4f%uff44%uff45%uff4c%uff47%uff52%uff4f%uff55%uff50%uff1b%uff13%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff30%uff35%uff25%ue011%uff28%uff47%uff52%uff4f%uff55%uff50%uff0e%u56fe%uff17 %uff30%uff35%uff25%u5bf9%u5927%u9f20%u80a1%u9aa8%u7ec4%u7ec7%u4e2d%u7834%u9aa8%u7ec6%u80de%u6570%u91cf%u7684%u5f71%u54cd%u3002%uff4e%uff1d%uff15%uff0c%uff58%u73cb%u00b1%uff53%uff26%uff49%uff47%ue010%uff17 %uff34%uff48%uff45%uff45%uff46%uff46%uff45%uff43%uff54%uff4f%uff46%uff30%uff35%uff25%uff4f%uff4e%uff54%uff48%uff45%uff4e%uff55%uff4d%uff42%uff45%uff52%uff4f%uff46%uff4f%uff53%uff54%uff45%uff4f%uff43%uff4c%uff41%uff53%uff54%uff53%uff49%uff4e%uff54%uff48%uff45%uff46%uff45%uff4d%uff4f%uff52%uff41%uff4c%uff54%uff49%uff53%uff53%uff55%uff45%uff4f%uff46%uff52%uff41%uff54%uff53%uff0e%uff4e%uff1d%uff15%uff0c%uff58%u73cb%u00b1%uff53%u4e0e %uff23%uff4f%uff4e%uff54%uff52%uff4f%uff4c%u7ec4%u6bd4%u8f83%uff0c%uff11%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff1b%u4e0e %uff2d%uff4f%uff44%uff45%uff4c%u7ec4%u6bd4%u8f83%uff0c%uff12%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff1b%u4e0e %uff30%uff35%uff25%ue011%uff28%u7ec4%u6bd4%u8f83%uff0c%uff13%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%u3002%uff11%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff43%uff4f%uff4e%uff54%uff52%uff4f%uff4c%uff47%uff52%uff4f%uff55%uff50%uff1b%uff12%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff4d%uff4f%uff44%uff45%uff4c%uff47%uff52%uff4f%uff55%uff50%uff1b%uff13%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff30%uff35%uff25%ue011%uff28%uff47%uff52%uff4f%uff55%uff50%uff0e%u56fe %uff18 %uff30%uff35%uff25%u5bf9%u5927%u9f20%u80a1%u9aa8%u7ec4%u7ec7%u4e2d %uff4d%uff49%uff32%uff2e%uff21%ue011%uff12%uff11%ue011%uff15%uff50%u3001%uff34%uff27%uff26%ue011%u03b2%uff11%u3001%uff33%uff4d%uff41%uff44%uff53%uff4d%uff32%uff2e%uff21%u8868%u8fbe%u7684%u5f71%u54cd%u3002%uff4e%uff1d%uff15%uff0c%uff58%u73cb%u00b1%uff53%uff26%uff49%uff47%ue010%uff18 %uff34%uff48%uff45%uff45%uff46%uff46%uff45%uff43%uff54%uff4f%uff46%uff30%uff35%uff25%uff4f%uff4e%uff54%uff48%uff45%uff4d%uff32%uff2e%uff21%uff45%uff58%uff50%uff52%uff45%uff53%uff53%uff49%uff4f%uff4e%uff4f%uff46%uff4d%uff49%uff32%uff2e%uff21%ue011%uff12%uff11%ue011%uff15%uff50%uff0c%uff34%uff27%uff26%ue011%u03b2%uff11%uff41%uff4e%uff44%uff33%uff4d%uff41%uff44%uff53%uff49%uff4e%uff54%uff48%uff45%uff46%uff45%uff4d%uff4f%uff52%uff41%uff4c%uff54%uff49%uff53%uff53%uff55%uff45%uff4f%uff46%uff52%uff41%uff54%uff53%uff0e%uff4e%uff1d%uff15%uff0c%uff58%u73cb%u00b1%uff53%uff12%ue010%uff17 %u5404%u7ec4%u5927%u9f20 %uff34%uff27%uff26%ue011%u03b2%uff11%uff0f%uff33%uff4d%uff41%uff44%uff53%u4fe1%u53f7%u901a%u8def%u86cb%u767d%u8868%u8fbe%u6bd4%u8f83%u5982%u56fe %uff19%u6240%u793a%uff0c%u4e0e %uff23%uff4f%uff4e%uff54%uff52%uff4f%uff4c%u7ec4%u76f8%u6bd4%uff0c%uff2d%uff4f%uff44%uff45%uff4c%u7ec4%u5927%u9f20%u80a1%u9aa8%u7ec4 %u7ec7 %u4e2d %uff34%uff27%uff26%ue011%u03b2%uff11%u3001%uff50%ue011%uff33%uff4d%uff41%uff44%uff12%uff0f%uff13%u8868 %u8fbe %u91cf %u660e %u663e %u964d %u4f4e%u3001%uff33%uff4d%uff41%uff44%uff17%u86cb%u767d%u8868%u8fbe%u6c34%u663e%u8457%u4e0a%u5347%uff08%uff30%uff1c%uff10%ue010%uff10%uff15%uff09%uff1b%u968f%u7740 %uff30%uff35%uff25%u5242%u91cf %u7684 %u589e %u52a0%uff0c%uff30%uff35%uff25%ue011%uff2c%u3001%uff30%uff35%uff25%ue011%uff28 %u7ec4 %u5927 %u9f20 %u80a1 %u9aa8 %u7ec4 %u7ec7 %u4e2d%uff34%uff27%uff26%ue011%u03b2%uff11%u3001%uff50%ue011%uff33%uff4d%uff41%uff44%uff12%uff0f%uff13%u8868%u8fbe%u91cf%u663e%u8457%u5347%u9ad8%u3001%uff33%uff4d%uff41%uff44%uff17%u86cb%u767d%u8868%u8fbe%u6c34 %u660e %u663e %u964d %u4f4e %uff08%uff30%uff1c%uff10%ue010%uff10%uff15%uff09%uff1b%u4e0e %uff30%uff35%uff25%ue011%uff28 %u7ec4 %u76f8 %u6bd4%uff0c%uff30%uff35%uff25%ue011%uff28%uff0b%uff24%uff49%uff53%uff49%uff54%uff45%uff52%uff54%uff49%uff44%u7ec4 %u5927 %u9f20 %u80a1 %u9aa8 %u7ec4 %u7ec7 %u4e2d %uff34%uff27%uff26%ue011%u03b2%uff11%u3001%uff50%ue011%uff33%uff4d%uff41%uff44%uff12%uff0f%uff13%u8868%u8fbe%u91cf%u660e%u663e%u964d%u4f4e%u3001%uff33%uff4d%uff41%uff44%uff17%u86cb%u767d%u8868%u8fbe%u6c34%u663e%u8457%u4e0a%u5347%uff08%uff30%uff1c%uff10%ue010%uff10%uff15%uff09%u3002TGF-%u03b21 p-Smad 2/3 Smad 700.51.01.5Expression levels of related proteinsControl groupModel groupPUE-L groupPUE-H groupPUE-H+Disitertide group1)2)2)3) 3)2)3)2)3)3)3)1)1)2)2)%u4e0e %uff23%uff4f%uff4e%uff54%uff52%uff4f%uff4c%u7ec4%u6bd4%u8f83%uff0c%uff11%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff1b%u4e0e %uff2d%uff4f%uff44%uff45%uff4c%u7ec4%u6bd4%u8f83%uff0c%uff12%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff1b%u4e0e %uff30%uff35%uff25%ue011%uff28%u7ec4%u6bd4%u8f83%uff0c%uff13%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%u3002%uff11%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff43%uff4f%uff4e%uff54%uff52%uff4f%uff4c%uff47%uff52%uff4f%uff55%uff50%uff1b%uff12%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff4d%uff4f%uff44%uff45%uff4c%uff47%uff52%uff4f%uff55%uff50%uff1b%uff13%uff09%uff30%uff1c%uff10%ue010%uff10%uff15%uff0c%uff43%uff4f%uff4d%uff50%uff41%uff52%uff45%uff44%uff57%uff49%uff54%uff48%uff54%uff48%uff45%uff30%uff35%uff25%ue011%uff28%uff47%uff52%uff4f%uff55%uff50%uff0e%u56fe %uff19 %uff30%uff35%uff25%u5bf9%u5927%u9f20%u80a1%u9aa8%u7ec4%u7ec7%u4e2d %uff34%uff27%uff26%ue011%u03b2%uff11%uff0f%uff33%uff4d%uff41%uff44%uff53%u901a%u8def%u6709%u5173%u86cb%u767d%u8868%u8fbe%u7684%u5f71%u54cd%u3002%uff4e%uff1d%uff15%uff0c%uff58%u73cb%u00b1%uff53%uff26%uff49%uff47%ue010%uff19 %uff34%uff48%uff45%uff45%uff46%uff46%uff45%uff43%uff54%uff4f%uff46%uff30%uff35%uff25%uff4f%uff4e%uff54%uff48%uff45%uff45%uff58%uff50%uff52%uff45%uff53%uff53%uff49%uff4f%uff4e%uff4f%uff46%uff34%uff27%uff26%ue011%u03b2%uff11%uff0f%uff33%uff4d%uff41%uff44%uff53%uff50%uff41%uff54%uff48%uff57%uff41%uff59%uff0d%uff52%uff45%uff4c%uff41%uff54%uff45%uff44%uff50%uff52%uff4f%uff54%uff45%uff49%uff4e%uff53%uff49%uff4e%uff52%uff41%uff54%uff46%uff45%uff4d%uff4f%uff52%uff41%uff4c%uff54%uff49%uff53%uff53%uff55%uff45%uff0e%uff4e%uff1d%uff15%uff0c%uff58%u73cb%u00b1%uff53%uff13 %u8ba8 %u8bba%uff2f%uff30%u662f%u4e00%u79cd%u6162%u6027%u75be%u75c5%uff0c%u968f%u7740%u8001%u9f84%u5316%u4eba%u53e3%u7684%u5feb%u901f%u589e%u957f%uff0c%u672a%u6765 %uff2f%uff30%u60a3%u8005%u7684%u6570%u91cf%u5c06%u7ee7%u7eed%u589e%u52a0%u3002%u8fd1%u5e74%u6765%uff0c%u4e2d%u8349%u836f%u53ca%u5176%u6d3b%u6027%u6210%u5206%u9010%u6e10%u88ab%u5e7f%u6cdb%u7528%u6765%u6cbb%u7597%u591a%u79cd%u91cd%u75c7%u75be%u75c5%uff3b%uff11%uff13%uff3d%u3002%uff30%uff35%uff25%u662f%u4e00%u79cd%u5bf9%u9aa8%u9abc%u5065%u5eb7%u6709%u76ca%u7684%u5f02%u9ec4%u916e%uff0c%u5728%u9884%u9632%u9aa8%u91cf%u6d41%u5931%u3001%u964d%u4f4e%u60a3 %uff2f%uff30%u98ce%u9669%u65b9%u9762%u53d1%u6325%u91cd%u8981%u4f5c%u7528%uff3b%uff11%uff14%uff3d%u3002%u00b7%uff11%uff19%uff12%uff18%u00b7 %uff23%uff48%uff49%uff4e%uff30%uff48%uff41%uff52%uff4d%uff2a%uff0c%uff12%uff10%uff12%uff15%uff33%uff45%uff50%uff54%uff45%uff4d%uff42%uff45%uff52%uff0c%uff36%uff4f%uff4c%ue010%uff16%uff10%uff2e%uff4f%ue010%uff11%uff18 %u4e2d%u56fd%u836f%u5b66%u6742%u5fd7 %uff12%uff10%uff12%uff15%u5e74 %uff19%u6708%u7b2c %uff16%uff10%u5377%u7b2c %uff11%uff18%u671f
                                
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