Effect of δ-Viniferin and Acetyl δ-viniferin on Microcirculation of Mice Auricle

M Ding;WNG Sho;KONG De-ning;WEI Y-hui

Chinese Pharmaceutical Journal ›› 2011, Vol. 46 ›› Issue (5) : 348-352.

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PDF(583 KB)
Chinese Pharmaceutical Journal ›› 2011, Vol. 46 ›› Issue (5) : 348-352.

Effect of δ-Viniferin and Acetyl δ-viniferin on Microcirculation of Mice Auricle

  • MA Ding,WANG Shao,KONG De-ning, WEI Ya-hui*
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Abstract

OBJECTIVE To study the effects of resveratrol,δ-viniferin and acetyl δ-viniferin on the microcirculation of mice auricle. METHODS Mice were administered drugs by ip.Blood velocity, capillary diameter, and the number of dilatation of capillary in microcirculation before and after injection were recorded. RESULTS δ-viniferin and acetyl δ-viniferin enlarged the diameter, increased dilatancy numbers and accelerate the blood velocity of mice auricle vein and the artery. CONCLUSION The experiment result shows that δ-viniferin and acetyl δ-viniferin can ameliorate the auricle microcirculation in mice, thus may have positive role in the treatment of microcirculation disturbance.

Key words

resveratrol / δ-viniferin / acetyl δ-viniferin / microcirculation

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M Ding;WNG Sho;KONG De-ning;WEI Y-hui. Effect of δ-Viniferin and Acetyl δ-viniferin on Microcirculation of Mice Auricle[J]. Chinese Pharmaceutical Journal, 2011, 46(5): 348-352

References


[1] GEHM B D, CHIEN P Y, JAMESON J L, et al. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor [J]. Proc Natl Acad Sci, 1997, 94(25: 14138-14143.
[2] CICHEMICZ R, KOUZIS A. Studies in natural products chemistry (Part G; attaur-rahman, Ed [J]. Amsterdam, 2002, 26(9: 507-579.
[3] LEE S H, SHIN N H, KANG S, et al. α-Viniferin: a prostaglandin H2 synthase inhibitory from root of Carex humilis [J]. Planta Med,1998, 64(7: 204-207.
[4] WANG Q F, LI J M, HUANG M J. Research on biological activity of grape pigment [J]. Sino-Overseas Grapevine & Wine(中外葡萄与葡萄酒, 2008,29(4: 46-50.
[5] ERTENLI I,KIRAZ S,OZTURK M A,et al.Pathologic throm bopoiesis of rheumatoid arthritis [J]. Rheumatol Int, 2003, 23 (2:49-60.
[6] WANG B Y, LI Y K. Chinese Herbal Medicine Developed Techniques and Methods(中药新药研制开发技术与方法[M]. Shanghai: Shanghai Scientific & Technological Publishing House, 2001:567-567.
[7] LI Y K. Chinese Medicine Pharmacology Experimental Methods 2nd ed.(中药药理实验方法学[M]. 2nd ed. Shanghai: Shanghai Scientific & Technological Publishing House, 2006:379-380.
[8] PRIVAT C, TELO J P, BERNARRDESCENISSION V, et al. Antioxidant properties of trans-epsilon- viniferin as compared to stilbene derivatives in aqueous and nonaqueous media [J]. Agric Food Chem, 2002, 50(5: 1213-1217.
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