Isolation and Structure Identification of Several Chemical Constituents in Gorgonian Verrucella sp.

WNG Wei;XU Shi-hi;LIO Xio-jin

Chinese Pharmaceutical Journal ›› 2010, Vol. 45 ›› Issue (3) : 172-174.

PDF(408 KB)
PDF(408 KB)
Chinese Pharmaceutical Journal ›› 2010, Vol. 45 ›› Issue (3) : 172-174.

Isolation and Structure Identification of Several Chemical Constituents in Gorgonian Verrucella sp.

  • WANG Wei, XU Shi-hai*, LIAO Xiao-jian
Author information +
History +

Abstract

OBJECTIVE To isolate and identify the chemical constituents in gorgonian Verrucella sp.METHODS Chromatography and recrystallization were performed for the isolation and purification, the structures were determined by extensive spectroscopic analysis in association with physical and chemical properties. RESULTS Seven compounds were isolated from the CH3COOCH2CH3 extracts of gorgonian Verrucella sp., their structures were identified as junceellin(1), praelolide (2), cholesterol(3), (E)-N-2-(1,3-dihydroxy octadecan-4-en)-hexadecamide(4), thymine(5), thymidine(6) and batyl alcohol(7). CONCLUSION All the compounds were isolated from the gorgonian for the first time.

Key words

gorgonian / Verrucella sp. / chemical constituents

Cite this article

Download Citations
WNG Wei;XU Shi-hi;LIO Xio-jin. Isolation and Structure Identification of Several Chemical Constituents in Gorgonian Verrucella sp.[J]. Chinese Pharmaceutical Journal, 2010, 45(3): 172-174

References


[1] LIAW C C, SHEN Y C, LIN Y S, et al. Frajunolides E-K, briarane diterpenes from Junceella fragilis[J]. J Nat Prod, 2008, 9(71):1551-1556.
[2] PAN Y C, ZENG L M. Extraction and separation of antitumor substances in marine corals [J]. J Instr Anal(分析测试学报) , 2006, 1(25):133-138.
[3] SUBRAHMANYAM C, KULATHEESWARAN R, WARD R S. Briarane diterpenes from the Indian ocean gorgonian Gorgonella umbraculum[J]. J Nat Prod, 1998, 9(61):1120-1122.
[4] LUO Y K, LONG K H, FANG Z. Studies on the chemical constituents of the Chinese gorgonia (Ⅲ): Isolation and identification of a new polyacetoxy Chlorine-containing diterpene lactone (praelolide) [J]. Acta Sci Nat Univ Sunyatseni(中山大学学报:自然科学版) , 1983,22(1): 83-92.
[5] YANG J, QI S H, ZHANG S, et al. Chemical constituents from the south China sea gorgonian coral Subergorgia reticulata[J].J Chin Med Mater(中药材) , 2006, 29(6):555-557.
[6] LI R S, LIU Q. Studies on the chemical constituents of the Chinese soft coral (Ⅲ Ⅹ Ⅵ) structures of two ceramides [J]. Chin J Mar Drugs(中国海洋药物), 1996,15(3):10-13.
[7] LIAO X J, XU S H, HUANG Q C, et al. Studies on chemical constituents from Callyspongia fibrosa(Ⅰ) [J]. Chin J Spectrosc Lab (光谱实验室), 2005, 22(2):281-283.
[8] SONG F H, FAN X, XU X L, et al. Studies on the chemical constituents of the marine sponge Tedania sp.[J]. Chin J Mar Drugs (中国海洋药物), 2004,23(3):11-14.
[9] HE X X, SU J Y, ZEN L M, et al. Studied on chemical constitution of Sinularia simpsoni Tix-Dur.[J]. Nat Prod Res Dev(天然产物研究与开发), 2001,13(2):14-15.
PDF(408 KB)

66

Accesses

0

Citation

Detail

Sections
Recommended

/