Studies on Chemical Constituents of Angelica polymorpha Maxim.
YANG Yu，YU Neng-jiang，ZHANG Yang，REN Feng-xia，ZHANG Ai-jun，ZHAO Yi-min*
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Institute of Pharmacology and Toxicology，Academy of Military Medical Sciences，Beijing 100850， China
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History+
Received
Revised
Published
2012-01-01
2012-01-01
2012-01-01
Issue Date
2010-09-05
Abstract
OBJECTIVE To study the chemical constituents of Angelica polymorpha Maxim. METHODS The chloroform-soluble fraction of alcohol-extract was isolated and purified by column chromatography on silicagel，RP-18 and Sephadex LH-20 column. All compounds were identified on the basis of spectral analysis and physico-chemical characters. RESULTS Thirteen compounds were isolated and identified as isoimperatorin (1)，aviprin (2)，angeliticin A (3)，bergapten (4)，imperatorin (5)，ledebouriellol (6)，columbianadin (7)，isopimpinellin (8) ，osthol (9) ，3′(R)-+-hamaudol (10) ，oxypeucedanin ethanolate (11) ，β-sitosterol (12) and stiamasterol (13). CONCLUSION Compounds 6-11 were isolated from this plant for the first time. Compound 6 and 11 were isolated from this genus for the first time.
YNG Yu;YU Neng-jing;ZHNG Yng;REN Feng-xi;ZHNG i-jun;ZHO Yi-min.
Studies on Chemical Constituents of Angelica polymorpha Maxim.[J]. Chinese Pharmaceutical Journal, 2010, 45(17): 1320-1322
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References
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