Antioxidant Effects of Polyphenols Constituents of Grape Seed in Mice

LIU Xing-rong;DENG Yin-hu;LIU Wen;DI Ying-chun

Chinese Pharmaceutical Journal ›› 2010, Vol. 45 ›› Issue (11) : 835-837.

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PDF(498 KB)
Chinese Pharmaceutical Journal ›› 2010, Vol. 45 ›› Issue (11) : 835-837.

Antioxidant Effects of Polyphenols Constituents of Grape Seed in Mice

  • LIU Xiang-rong，DENG Yin-hua，LIU Wen， DAI Ying-chun
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Abstract

OBJECTIVE To investigate the antioxidant effects of polyphenols constituents of grape seed in Mice. METHODS Subacute intoxication induced aging Kunming mice model injected subcutaneously with 40 mg·kg-1·d-1 D-gal were divided into model control group and high，middle，low dosage of polyphenols constituents of grape seed (40，20，10 mg·kg-1·d-1)，while the blank and model group were treated with normal Saline. RESULTS Polyphenols constituents of grape seed improved the activities of SOD and GSH-PX， and obviously increased the levels of MDA in the blood， liver and brain of rats. CONCLUSION Polyphenols constituents of grape seed have the antioxidant efficiency.

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grape seed / polyphenols constituents / rats / antioxidant

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LIU Xing-rong;DENG Yin-hu;LIU Wen;DI Ying-chun . Antioxidant Effects of Polyphenols Constituents of Grape Seed in Mice[J]. Chinese Pharmaceutical Journal, 2010, 45(11): 835-837

References


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