Abstract
OBJECTIVE To study the chemical constituents of Phlomis medicinalis Diels.METHODS The compounds were isolated and repeatedly purified by macroporous resin,silica gel column chromatography,TLC and Prep-HPLC.Their structures were elucidated by physical and chemical properties and NMR spectra.RESULTS Seven compounds were obtained and elucidated as pulchellosideⅠ(Ⅰ),lamalbide(Ⅱ),7-epiphlomiol(Ⅲ),penstemoside(Ⅳ),β-dihydrohastatoside(Ⅴ),phloyosideⅢ(Ⅵ),decaffeoylacteoside(Ⅶ).CONCLUSION All the compounds were isolated from the plant for the first time.Compound Ⅴ and Ⅶ were obtain-ed from the Plants of Phlomis for the first time.
Key words
Phlomis medicinalis /
chemical constituents /
iridoid glucosides
{{custom_keyword}} /
Cite this article
Download Citations
XUE Heng-yue;WNG Gng-li;LI Ping;LIN Rui-cho.
Studies on Chemical Constituents of Phlomis medicinalis(Ⅳ) [J]. Chinese Pharmaceutical Journal, 2008, 43(10): 739-741
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] The Editorial Board of Flora China,Chinese Academy of Science.Flora of China(中国植物志)[M] . Vol 65(2). Beijing:Science Press,1977: 448-449.
[2] Qinghai Institute for Drug Control,Qinghai Tibetan Medicine Resea- rch Institute. China Tibetan Medicine(中国藏药) [M] . Vol 3. Shanghai : Science and Technique Publishing Company of Shanghai,1996:310-311.
[3] State Administration of Traditional Chinese Medicine. China Herbal(中华本草) [M] . Vol 19. Shanghai : Science and Technique Publishing Company of Shanghai,1999:128-129.
[4] YU Z X,WANG G L,BIANBA C R,et al. Studies on chemical con- stituents in root of Phlomis medicinalisⅠ[J] . China J Chin Mater Med (中国中药杂志),2006,31(8):656-658.
[5] EL-HELA A A,SOWINSKI P,KRAUZE-BARANOWSKA M. Irid- oids and phenylethanoids of Verbena bipinnatifida nutt[J] . Acta Pol Pharm,2000,57(1): 65-68.
[6] ERSOZ T,SCHUHLY W,POPOV S,et al. Iridoid and phenyleth- anoid glycosides from Phlomis longifolia var. Longifolia[J] . Nat Prod Lett,2001,15(5):345-351.
[7] ZHANG C Z,LI C,FENG S J,et al. Iridoid glucosides from Phlomis rotata[J] . Phytochemistry,1991,30(12) :4156-4158.
[8] THOMAS B,SOREN D,SOREN R J,et al. Iridoid glucosides from Pedicularis[J] . Phytochemistry,1985,24(3):491-493.
[9] BOROS C A,STERMITZ F R.Iridoids,An updated review[J] . J Nat Prod,1990,53:1055-1147.
[10] LI C,ZHANG C G. Study the chemical constituents from Phlomis mongolica Turcz(Ⅱ)[J] . China J Chin Mater Med(中国中药杂志),2000,25(1):35-37.
[11] KARASAWA H,KOBAYASHI H,TAKIZAWA N,et al. Studies on the constituents of Cistanchis herba. Ⅷ. Isolation and structures of cistanosides H and I[J] . Yakugaku Zasshi,1986,106(3):562-566.
{{custom_fnGroup.title_en}}
Footnotes
{{custom_fn.content}}