微乳体系对药物吸收、分布和药动学的影响

Chinese Pharmaceutical Journal ›› 2008, Vol. 43 ›› Issue (10) : 723-726.

Chinese Pharmaceutical Journal ›› 2008, Vol. 43 ›› Issue (10) : 723-726.
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[1] KIM C K,CHO Y J,GAO Z G. Preparation and evaluation of biphenyl dimethyl dicarboxylate microemulsions for oral delivery[J] . J Controlled Release,2001,70 (1-2):149-155. [2] SUBRAMANIAN N,RAY S,GHOSAL S K,et al. Formulation design of self-microemulsifying drug delivery systems for improved oral bioavailability of celecoxib[J] . Biol Pharm Bull,2004 ,27 (12):1993-1999. [3] ARAYA H,TOMITA M,HAYASHI M,et al. The novel formulation design of O/W microemulsion for improving the gastrointestinal absorption of poorly water soluble compounds[J] . Int J Pharm,2005 ,305(1-2):61-74. [4] LU Y,JIANG X S,ZENG R J. Pharmacokinetics of diclofenac sodium microemulsions in rabbits[J] . Acad J Sec Mil Med Univ (第二军医大学学报),2000,21 (10): 980-982. [5] LU Y,JIANG X S,ZENG R J,et al. Pharmacokinetics of diclofenac sodium microemulsion in human[J] . Acad J Sec Mil Med Univ (第二军医大学学报),2001,22 (4):364-366. [6] WANG L,DENG J,JIN Y Y,et al. Comparation of anticoagulation effects of low molecular weight heparin(LMWH) nano-liposomes and microemulsions in rat by oral administration[J] . Jiangsu Pharm Clin Res(江苏药学与临床研究),2005,13 (2):4-6. [7] LYONS K C,CHARMAN W N,MILLER R,et al. Factors limiting the oral bioavailability of N-acetylglucosaminyl-N- acetylmuramyl dipeptide (GMDP) and enhancement of absorption in rats by delivery in a water-in-oil microemulsion[J] .Int J Pharm,2000,199 (1):17-28. [8] MENG B Y,PING Q N,XIONG J,et al. Hypoglycemic effect of insulin W/O microemulsions following intestinal administration to rats[J] . J China Pharm Univ(中国药科大学学报),2006,37 (4):304-330. [9] DUNN C J,WAGSTAFF A J,PERRY C M,et al. Cyclosporin:an updated review of the pharmacokinetic properties,clinical efficacy and tolerability of a microemulsion-based formulation (neoral)1 in organ transplantation[J] . Drugs,2001,61(13):1957-2016. [10] BARALDO M,PEA F,POZ D,et al. Pharmacokinetics of two oral cyclosporine A formulations in clinically stable heart-transplant patients[J] .Pharmacol Res,2001 ,43 (6):547-551 . [11] GHORAB M M. Accelerated oral absorption of ibuprofen in human subjects from soft gelatin capsules containing microemulsion pre-concentrate [J] . Bull Faculty Pharm,2002,40 (1):193-200. [12] KAWAKAMI K,YOSHIKAWA T,HAYASHI T,et al. Microemulsion formulation for enhanced absorption of poorly soluble drugs Ⅱ in vivo study[J] .J Controlled Release,2002 ,81(1-2):75-82. [13] CHEN H B,WENG T,CHANG X L,et al. Preparation of ibuprofen microemulsion and its transdermal absorption[J] .Chin Pharm J(中国药学杂志),2004,39 (1):43-45. [14] KREILGAARD M. Influence of microemulsions on cutaneous drug delivery[J] . Adv Drug Deliv Rev,2002,54 (1):77-98. [15] PELTOLA S,SAARINEN-SAVOLAINEN P,KIESVAARA J,et al. Microemulsions for topical delivery of estradiol[J] .Int J Pharm,2003 ,254 (2):99-107. [16] WU H,RAMACHANDRAN C,WEINER N D,et al. Topical transport of hydrophilic compounds using water-in oil nanoemulsiond[J] .Int J Pharm,2001,220 (1-2):63-75. [17] PAOLINO D,VENTURA C A,NISTICO S,et al. Lecithin microemulsions for the topical administration of ketoprofen:percutaneous adsorption through human skin and in vivo human skin tolerability[J] .Int J Pharm,2002,244 (1-2):21-31. [18] GETIE M,WOHLRAB J,NEUBERT R H. Dermal delivery of desmopressin acetate using colloidal carrier systems [J] .J Pharm Pharmacol,2005 ,57(4):423-427. [19] LEE P J,LANGER R,SHASTRI V P. Novel microemulsion enhancer formulation for simultaneous transdermal delivery of hydrophilic and hydrophobic drugs[J] .Pharm Res,2003,20 (2):264-269. [20] NASSERI A A,ABOOFAZELI R,ZIA H,et al. Lecithin-stabilized microemulsion-based organogels for topical application of ketorolac tromethamine Ⅱ. In vitro release study [J] . Iran J Pharm Res,2003,2 (2):117-124. [21] SINTOV A C,SHAPIRO L. New microemulsion vehicle facilitates percutaneous penetration in vitro and cutaneous drug bioavailability in vivo[J] .J Controlled Release,2004,95 (2):173-183. [22] HASS A,KOIPERT S. Development and characterization of microemulsions for ocular application[J] . Eur J Pharm Biopharm,1997,439 (2):179-183. [23] ALANY R G,RADES T,NICOLL J,et al. W/O Microemulsions for ocular delivery:evaluation of ocular irritation and precorneal retention[J] .J Controlled Release,2006 ,111 (1-2):145-152. [24] JUNPING W,TAKAYAMA K,NAGAI T,et al. Pharmacokinetics and antitumor effects of vincristine carried by microemulsions composed of PEG-lipid,oleic acid,vitamin E and cholesterol[J] . Int J Pharm,2003,251 (1-2):13-21. [25] AZEVEDO C H,CARVALHO J P,VALDUGA C J,et al. Plasma kinetics and uptake by the tumor of a cholesterol-rich microemulsion (LDE) associated to etoposide oleate in patients with ovarian carcinoma[J] .Gynecol Oncol,2005,97(1):178-182. [26] TONG X Y,HUANG C Y,YAO J,et al. Distribution of nimodipine microemulsion in mice in vivo and evaluation on its targeting performance[J] . J China Pharm Univ(中国药科大学学报),2002,33 (4):293-296. [27] HE L,WANG G L,ZHANG Q. Studies on hypersensitivity and pharmacokinetics of paclitaxel microemulsion[J] .Acta Pharm Sin (药学学报),2003,38 (3):227-230. [28] LOCKMAN P R,KOZIARA J M,MUMPER R J. et al. Nanoparticle surface charges alter blood-brain barrier integrity and permeability[J] .J Drug Target,2004,12 (9-10):635-641. [29] ZHAO W,ZHANG X N. Application and investigation of drug nanoparticle-delivery-system in ophthalmology[J] .Chin Ophthalmic Res(眼科研究),2002,20 (2):186-189. [30] HWANG S R,LIM S J,PARK J S,et al. Phospholipid-based microemulsion formulation of all-trans-retinoic acid for parenteral administration[J] .Int J Pharm,2004 ,276 (1-2):175-183. [31] LAWRENCE M J,REES G D. Microemulsion-based media as novel drug delivery systems[J] .Adv Drug Deliv Rev,2000 ,45 (1):89-121. [32] POLLARD S,NASHAN B,JOHNSTON A,et al. Pharmacokinetic and clinical review of the potential clinical impact of using different for mulation of cydosporin A[J] .Clin Ther,2003 ,25 (6):1654-1669. [33] ZHANG L,XIANG D,HONG Z,et al. Studies on the liver targeting of norcantharindin microemulsion[J] .Acta Pharm Sin(药学学报),2004,39 (8):650-655. [34] FAWAZ F,BONINI F,MAUGEIN J,et al. Pharmacokinetics and in vitro antimicrobial ctivity ciprofloxacin-loaded polyisobutylcyanoacrylate nanoparticles[J] .Int J Pharm,1998,168 (2):255-259.

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