Effect of Different Composition in Maxingshigan Decoction on Contents of Glycyrrhizic Acid
HE Zhu-ying1，2，WU Kong-yun3，LIANG Guang-yi1*，JIN Feng-yun2，LI Xing2，FENG Hua2
Author information+
1.Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences，Guiyang 550002，China； 2.Guiyang College of Traditional Chinese Medicine，Guiyang 550002，China； 3.Guiyang College，Guiyang 550003，China
{{custom_zuoZheDiZhi}}
{{custom_authorNodes}}
{{custom_bio.content}}
{{custom_bio.content}}
{{custom_authorNodes}}
Collapse
History+
Received
Published
2007-04-11
2008-02-10
Issue Date
2008-02-10
Abstract
OBJECTIVE To inspect the effect of different composition in Maxingshigan Decoction on the contents of glycyrrhizic acid.METHODS Using the method of mixture-even-design-law,the licorice quantity was fixed in Maxingshigan Tang,the other raw materials(Herba Ephedrae,Semen Armeniacae Amarum,Gypsum Fibrosum)was taken as the in variable factor.The glycyrrhizic acid was measured and regression analysis was processed.RESULTS The regression equations were Y=5.634 604 20+3.819 566 922X1+1.493 484 653 7X3(r=0.831 93,P=0.029 2).Ephedra sinica was the main influent factor of the contents of glycyrrhizic acid in different compositions.CONCLUSION The dissolving rate of glycyrrhizic acid is proportional positively to the quantity of ephedrine.
HE Zhu-ying;WU Kong-yun;LING Gung-yi;JIN Feng-yun;LI Xing;FENG Hu.
Effect of Different Composition in Maxingshigan Decoction on Contents of Glycyrrhizic Acid [J]. Chinese Pharmaceutical Journal, 2008, 43(04): 264-267
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] ZHOU J L，WANG Y S.The Clinical Application and Research of Concentration Granule of Traditional Chinese Medicine[M] . Beijing：Peopl′s Medicinal Publishing House，1998：375.
[2] CHEN X M，The gypsum uses the deal′s importance in Maxingshigan Decoctio[J] .Sichuan J Tradit Chin Med（四川中医），2001，19（2）：78-81.
[3] Ch.P (2005)VolⅠ(中国药典2005年版第一部)[S] .2005：180-182.
[4] FANG K T，MA C X.Give to the Even and on Trial Design(正交与均匀试验设计)[M] . Beijing：Science Publishing House，2001：144-152.
[5] YU R Y ，YU Z. Study on learning and memorising of Yizhifang in ovariectomized mice by uniform design of experiments with mixtures[J] .Chin J Clin Pharmacol Ther（中国临床药理学与治疗学），2004，9 (6)：680-682.
[6] LIU J. Even design method is in the compound prescribe application for measuring the ratio thepick outing[J] .Chin Tradit Pat Med（中成药），1996，18(10)：3-5.
