Effect of Different Composition in Maxingshigan Decoction on Contents of Glycyrrhizic Acid

HE Zhu-ying;WU Kong-yun;LING Gung-yi;JIN Feng-yun;LI Xing;FENG Hu

Chinese Pharmaceutical Journal ›› 2008, Vol. 43 ›› Issue (04) : 264-267.

Chinese Pharmaceutical Journal ›› 2008, Vol. 43 ›› Issue (04) : 264-267.
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Effect of Different Composition in Maxingshigan Decoction on Contents of Glycyrrhizic Acid

  • HE Zhu-ying1,2,WU Kong-yun3,LIANG Guang-yi1*,JIN Feng-yun2,LI Xing2,FENG Hua2
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Abstract

OBJECTIVE To inspect the effect of different composition in Maxingshigan Decoction on the contents of glycyrrhizic acid.METHODS Using the method of mixture-even-design-law,the licorice quantity was fixed in Maxingshigan Tang,the other raw materials(Herba Ephedrae,Semen Armeniacae Amarum,Gypsum Fibrosum)was taken as the in variable factor.The glycyrrhizic acid was measured and regression analysis was processed.RESULTS The regression equations were Y=5.634 604 20+3.819 566 922X1+1.493 484 653 7X3(r=0.831 93,P=0.029 2).Ephedra sinica was the main influent factor of the contents of glycyrrhizic acid in different compositions.CONCLUSION The dissolving rate of glycyrrhizic acid is proportional positively to the quantity of ephedrine.

Key words

Maxingshigan decoction / mixed uniform design / glycyrrhizic acid

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HE Zhu-ying;WU Kong-yun;LING Gung-yi;JIN Feng-yun;LI Xing;FENG Hu. Effect of Different Composition in Maxingshigan Decoction on Contents of Glycyrrhizic Acid [J]. Chinese Pharmaceutical Journal, 2008, 43(04): 264-267

References

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