1.National Institute for the Control of Pharmaceutical and Biological Products，Beijing 100050，China；2.Yunnan Provincial Institute for Foodstuff & Drug Control，Kunming 650011，China；3.Zhejiang Tianrui Pharmaceutical Co.Ltd，Ruian 325200，China
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History+
Received
Published
2006-12-20
2008-02-05
Issue Date
2008-02-05
Abstract
OBJECTIVE To establish a HPLC method for the determination of three constituents curdione,curcumol and germacrone in zedoary turmeric oil injection.METHODS The sample was analyzed on SHIMADZU VP-ODS C18(4.6 mm×250 mm,5 μm)column with mobile phase consisting of 0.1% phosphoric acid and acetonitrile by gradient eluteion at the flow rate of 1.0 mL·min-1.The wavelength was at 210 nm.RESULTS The good linearity,recovery and reproducibility were obtained.The mean recoveries were above 99.0% and RSDs were below 20%.CONCLUSION The method is simple,quick to process and accurate,and can be used for quality control for zedoary turmeric oil injection.
YUN Wen-Jun;TIN Song-Jiu;ZHNG Qi-ming;LI Hui-yi;CUI You.
Determination of Four Constituents in Oleum Curcumae And Zedoary Turmeric Oil Injection by HPLC [J]. Chinese Pharmaceutical Journal, 2008, 43(03): 168-170
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References
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