Determination of Organophosphorus Pesticides in Flos Lonicerae Japonicae by SPE GC/MS
HE Xiao-rong1,ZOU Ding1,FENG Jin-hong2,WU Xue-jun1,HU Xin1,SUN Chun-hua1
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1.Department of Pharmacy,Beijing Hospital,Ministry of Health ,Beijing 100730,China;2.School of Pharmacy,Shangdong University,Jinan 250012,China
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Received
Published
2006-11-17
2007-12-10
Issue Date
2007-12-10
Abstract
OBJECTIVE To establish an analytical method for the determination of 14 kinds of organophosphate pesticide residues in Flos Lonicerae Japonicae by solid-phase extraction(SPE) and Gas Chromatograph-mass spectrometry.METHODS Ultrasonication with acetone in ice bath was used for sample preparation.The sample was processed by SPE column added with 0.2 g active carbon.The total ion current(TIC)was identified with a spectrum library search.Selected ion monitoring(SIM)was used as quantify.RESULTS All the organophosphate pesticide showed good linearity in a detected concentration range with good correlation coefficient(r=0.980 2~1.000 0).The method recoveries were generally 65.02%~107.04% with RSD 3.6%~8.0% and the limit of detection was 0.017 9~0.092 5 ppm(S/N =3).CONCLUSION The method is effective,fast,accurate and provide an analytical method of the organophosphate pesticide residue in traditional medicine.
HE Xio-rong;ZOU Ding;FENG Jin-hong;WU Xue-jun;HU Xin;SUN Chun-hu.
Determination of Organophosphorus Pesticides in Flos Lonicerae Japonicae by SPE GC/MS [J]. Chinese Pharmaceutical Journal, 2007, 42(24): 1901-1904
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