Abstract
OBJECTIVE To study chemical constituents of the tubers of Gymnadenia conopsea.METHODS The compounds were isolated by column chromatographic methods,their structures were elucidated on the basis of physical properties and spectral analysis.RESULTS Seven compounds were isolated from n-butanol extract of this plant and identified as di-(p-hydroxybenzyl) disulfide(Ⅰ),4,4′ -dihydroxybenzyl sulfoxide(Ⅱ),adenosine(Ⅲ),militarine(Ⅳ),loroglossin(Ⅴ),dactylorhin B(Ⅵ) and dactylorhin A(Ⅶ).CONCLUSION CompoundⅠwas obtained from nature products for the first time,and compound Ⅱ was obtained from the plants of Gymnadenia R.Br. for the first time.
Key words
Gymnadenia conopsea /
chemical constituents /
di-(p-hydroxybenzyl) disulfide
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LI Min;GUO Shun-xing;WNG Chun-ln;XIO Pei-gen.
Studies on Chemical Constituents of Tubers of Gymnadenia conopsea[J]. Chinese Pharmaceutical Journal, 2007, 42(22): 1696-1698
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References
[1] The Editorial Board of Flora of China，Chinese Academy of Science.Flora of China(中国植物志)[M] .Vol 17.Beijing:Science Press，1999:388-394.
[2] BUYUKLIEV R，POZHARLIEV I，KOEDZHIKOV A，et al.Synthesis of diaryl and di(arylmethyl) disulfides with hydrophilic substituents for use as additives to acid copper electrolytes[J] .Izvestiya Po Khimiya，1990，23(3):456-464.
[3] KAWAKISHI S，MURAMATSU K.Studies on the decomposition of sinalbin.Part I.The decomposition products of sinalbin[J] .Agr Biol Chem，1966，30(7):688-692.
[4] HYE S Y，MI K P.Isolation of 4,4′-dihydroxybenzyl sulfoxide from Gastrodia elata[J] .Arch Pharm Res，1997，20(1):91-92.
[5] DI Y T.Studies on the chemical constituents of Swertia mileensis and Gymnadeina conopsea[D] .Chengdu:Chengdu Institute of Biology，Chinese Academy of Science，2003.
[6] KIZU H，KANEKO E，TOMIMORI T. Studies on nepalese crude drugs.XXⅥ.Chemical constituents of panch aunle，the roots of Dactylorhiza hatagirea D.Don[J] .Chem Pharm Bull，1999，47(11):1618-1625.
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