DENG Xia-fei1，FENG Chang-gen1，ZHANG Tong-bin2，YANG Yan-qing2
Author information+
1.Beijing Institute of Technology，Beijing 100081，China；2.Hubei Gedian Humanwell Pharmaceutical Co. Ltd，Ezhou 436070，China
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History+
Received
Published
2005-12-09
2007-04-05
Issue Date
2007-04-05
Abstract
OBJECTIVE To study the synthetic process for 3-oxo-Δ4,6 steroids using 3-hydroxy-Δ5 steroids as starting materials.METHODS Using the bromine, the lithium bromide and the promoter pyridine carried out the oxidized dehydrogenation.RESULTS The target compound was obtained and purified yield was over 60%.CONCLUSION The process provides high yields with inexpensive cost and has one-step synthesis.
DENG Xi-fei;FENG Chng-gen;ZHNG Tong-in;YNG Yn-qing.
One-Step Synthesis of 3-oxo-Δ4,6 Steroids [J]. Chinese Pharmaceutical Journal, 2007, 42(07): 548-549
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References
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