Protective Effect of Punica granatum L.Against Rat Liver Microsomal Lipid Peroxidation

ZHOU en-hong;LIU Chun;WU Yue;WU Zhen-hu;LI Xio-jun;ZHNG Jie

Chinese Pharmaceutical Journal ›› 2006, Vol. 41 ›› Issue (24) : 1864-1865.

Chinese Pharmaceutical Journal ›› 2006, Vol. 41 ›› Issue (24) : 1864-1865.
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Protective Effect of Punica granatum L.Against Rat Liver Microsomal Lipid Peroxidation

  • ZHOU Ben-hong1,LIU Chun2,WU Yue2,WU Zhen-hua2,LI Xiao-jun2,ZHANG Jie1
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Abstract

OBJECTIVE To investigate the protective effect of Punica granatum L. on rat liver microsomal lipid peroxidation.METHODS The lipid peroxidation model of rat liver microsomal was manufactured by two kinds of systems,Vit C/Fe2+ and Cys/Fe2+. The content of malondialdehyde (MDA) was determined.RESULTS Compared with model group, all of the Punica granatum L.groups dose-dependently inhibited the increases of MDA content in the rat liver microsomal lipid peroxidationinduced by Vit C/Fe2+ and Cys/Fe2+ system.CONCLUSION Punica granatum L. has protective effect against rat liver microsomal lipid peroxidation.

Key words

Punica granatum L. / liver microsome / lipidperoxidation

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ZHOU en-hong;LIU Chun;WU Yue;WU Zhen-hu;LI Xio-jun;ZHNG Jie. Protective Effect of Punica granatum L.Against Rat Liver Microsomal Lipid Peroxidation [J]. Chinese Pharmaceutical Journal, 2006, 41(24): 1864-1865

References

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