OBJECTIVE To develop a rapid on-line endpoint determination during Salviae miltiorrhiza extraction process by near infrared spectroscopy.METHODS With HPLC as a reference method, an approach was built for the endpoint determination for industrial production of Salviae miltiorrhiza based on the on-line near infrared spectroscopy and chemometrics.RESULTS This proposed method was demonstrated in industrial extraction process. The result is accurately confirmed by HPLC analysis. CONCLUSION This method is rapid, accurate, effective and applicable for the extraction process of Salviae miltiorrhiza.
SHI Cho-sheng;LIU Xue-song;CHEN Yong;QU Hi-in;CHENG Yi-yu.
Study on Rapid Endpoint Determination of Salviae miltiorrhiza Extraction Process [J]. Chinese Pharmaceutical Journal, 2006, 41(23): 1771-1773
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