OBJECTIVE To evaluate the bioequivalence of domestic finasteride tablet and imported tablet. METHODS A single oral dose of 10 mg domestic tablet or imported tablet was given to 20 healthy volunteers in a randomized crossover study. The concentrations of finasteride were determined by HPLC method. RESULTS The main pharmacokinetic parameters of the two products were as follows：AUQ_0-24(840.63±140.84) and (847.51±166.96) ng-h-mL^-1, c_max(117.17±19.74) and (117.43±18.06) ng·mL^-1, t_max(1.88±0.48) and (1.95±0.43)h，respectively. The relative bioavailability of domestic tablet to imported tablet was (100.73土15.27)%. There were no significant differences on the pharmacokinetic parameters between the two preparations(P>0.05). CONCLUSION The results demonstrated that the two preparations were bioequivalent.