Studies on regulation of Sini Tang on adrenegic receptors in cardiac function and blood pressure of hemorrhagic shock rats

SHO Chun-hong;WNG Xio-ling

Chinese Pharmaceutical Journal ›› 2003, Vol. 38 ›› Issue (11) : 847-850.

Chinese Pharmaceutical Journal ›› 2003, Vol. 38 ›› Issue (11) : 847-850.
药理

Studies on regulation of Sini Tang on adrenegic receptors in cardiac function and blood pressure of hemorrhagic shock rats

  • SHAO Chun-hong,WANG Xiao-liang
Author information +
History +

Abstract

OBJECTIVE To study the protective effect of Sini Tang on cardiac function of hemorrhagic shock rats. METHODS The effect of Sini Tang on hemodynamics of hemorrhagic shock rats and the influence of α and β receptors antagonists were observed. RESULTS Sini Tang improved the LVSP,(dp/dtmax and MAP of hemorrhagic shock rats,and the effects were inhibited by α and β receptors antagonists in different degrees. CONCLUSION Sini Tang can improve the cardiac function and increase the arterial blood pressure of hemorrhagic shock rats.The regulation of α and β receptors may involve in this process.

Key words

Sini Tang / hemodynamics / α receptor antagonist / β receptor antagonist

Cite this article

Download Citations
SHO Chun-hong;WNG Xio-ling. Studies on regulation of Sini Tang on adrenegic receptors in cardiac function and blood pressure of hemorrhagic shock rats[J]. Chinese Pharmaceutical Journal, 2003, 38(11): 847-850

References

[1]天津市南开医院.中西医结合治疗急性心肌梗塞99例的临床体会[J].新医药学杂志,1974,(3):117. [2]江京莉,周远鹏.附子的药理作用和毒性[J].中成药,1991;13(12):37. [3]周远鹏,刘文化.附子水溶部分对内毒素休克的治疗作用[J].中药通报,1988;13(5):43. [4]刘文化,周远鹏,曾贵云.去甲乌药碱对实验性心力衰竭的治疗作用[J].药学学报,1988,23(2):81. [5]冯亦璞,高红,曾贵云.去甲乌药碱对α肾上腺素受体的影响[J].中国药理学报,1986,7(3):208. [6]Konno C,Shirasaka,Hikino H.Cardioactive principle of aconitum carmichaeli roots.Planta Med,1979,35 (2 ):150. [7]陈迪华,梁晓天.中药附子成分研究.Ⅰ去甲猪毛菜碱(salsolinol)的分离及其结构测定[J].药学学报.1982,(10):792. [8]韩新明,丁建弥,杨藻震.四逆汤对麻醉家兔低血压状升压效应的初步拆方研究[J].中成药研究,1983,(2):26.

Accesses

Citation

Detail

Sections
Recommended

/