OBJECTIVE To study the contents of the effective conponent-ferulic acid in Shenghuatang and in other decotions composed of one or more ingredients of Shenghuatang.METHODS The contents of ferulic and were determined by reversed-phase high-performance liquid chromatography.RESULTS The freulic acid contents in the decoction of angelica sinensis and the decoction of ligusticum chuanxiong were 56.88±0.11 μg·g-1 and 36.2±4.0 μg·g-1, respectively; they varied from 1.71 mg·g-1 to 56.88 μg·g-1 among Shenghua Tang and the decoctions composed of two or three ingredients.CONCLUSIONS The content of ferulic acid in the decoction composed of angelica sinensis and ligusticum chuanxiong was the sum of that in the decoction of either of them; the contents of that decreased in the decoctions combined with semen persicae、Radix glycyrrhizae、Rhizoma zingiberis;the content of ferulic acid in Shenghuatang appeared to be the highest among all the relative decoctions.
Key words
Shenghuatang /
compatibility /
composition /
ferulic acid /
RP-HPLC
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References
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[2] 容蓉, 袁久荣, 王学志. HPLC测定四物汤及其配伍组方中阿魏酸的煎出量[J]. 中国药学杂志, 2000,35(11):767.
[3] 杨宁莲, 杨文远, 杨政红. 高效液相色谱法测定生化汤口服液中阿魏酸含量[J].中国医院药学杂志, 1999,19(2):88.
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Footnotes
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