Chemical studies on new xanthone from Swertia decora

.上海第二医科大学化学教研室;上海 000;.大理医学院药学系;云南 大理 000

Chinese Pharmaceutical Journal ›› 2001, Vol. 36 ›› Issue (05) : 302-304.

Chinese Pharmaceutical Journal ›› 2001, Vol. 36 ›› Issue (05) : 302-304.
中药及天然药物

Chemical studies on new xanthone from Swertia decora

  • 1.上海第二医科大学化学教研室，上海 200025；2.大理医学院药学系，云南 大理 671000
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Abstract

OBJECTIVE To study the chemical constituents of Swertia decora Franch,a traditional herb medication in China.METHODS The constituents were separated and purified by using column chromatography with silica gel.Their structures were identified on the basis of spectral analysis and chemical reactions. RESULTS Six compounds were isolated from the CHCl3part of the extracts.Their structures were determined as 1-hydroxy-4,5,6,7-tetramethoxyxanthone(swertiadecoraxanthoneⅠ)(Ⅰ),1,3,8-trihydroxy-2,5dimethoxyxanthone(Ⅱ),1,8-dihydroxy-3,7-dimethoxy xanthone (methylswertianin,Ⅲ),1-hydroxy-3,7,8-trimethoxyxanthone (decussatin,Ⅳ),1,7,8-trihydroxy-3methoxyxanthone(swertianin,Ⅴ) and tetracosanoic acid(Ⅵ),respectively.CONCLUSION Ⅱ named as swertiadecoraxanthoneⅡ was a new compound and the others were found from this plant for the first time.

Key words

Swertia decora / gentianaceae / xanthone / swertiadecoraxanthone-Ⅱ

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.上海第二医科大学化学教研室;上海 000;.大理医学院药学系;云南 大理 000. Chemical studies on new xanthone from Swertia decora[J]. Chinese Pharmaceutical Journal, 2001, 36(05): 302-304

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