Preliminary observations on the stability of phospholipid capsules

He Xinxi

Chinese Pharmaceutical Journal ›› 1999, Vol. 34 ›› Issue (08) : 538-540.

Chinese Pharmaceutical Journal ›› 1999, Vol. 34 ›› Issue (08) : 538-540.
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Preliminary observations on the stability of phospholipid capsules

  • He Xinxia
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Abstract

OBJECTIVE: The stability of phospholipid capsules was preliminarily studied. METHOD: The appearance,disintegration time,color of alcohol solution,content and degradation products were observed and analyzed under the test of influencing factors,accelerating test,inspecting test at room temperature and low temperarure,respectively.And the results were compared with those at 0 hour. RESULTS: Under 60, the capsules became deformed and broken.The color of the content became dark.The degradation products appeared at the tenth day.Under 40 with RH 75%,degradation products appeared.The color of content became dark in the first month,the second month and the third month, respectively.disintegration time was prolonged in the third month. CONCLUSION: The phospholipid capsules were unstable at high temperature and high hAuthor umidity, but stable under other inspecting conditions.

Key words

phospholipid / capsules / stability test

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He Xinxi. Preliminary observations on the stability of phospholipid capsules[J]. Chinese Pharmaceutical Journal, 1999, 34(08): 538-540

References

1 蒋兴仁.国外磷脂健康食品介绍.食品工业科技,1990,(4):12. 2 浙江省卫生厅编.浙江省药品标准1993年版.1993:301. 3 中国药典1995年版.二部:附录17. 4 Marinentti G V.Lipid Chromatographic Analysis Volume 3.2nd ed.New York:Marceldekker INC.1976:760.

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